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弥散性血管内凝血与D-二聚体检测结果阴性

Disseminated intravascular coagulation and a negative D-dimer test.

作者信息

Constantinescu A A, Berendes P B, Levin M-D

机构信息

Department of Internal Medicine, Albert Schweitzer Hospital, Location Dordwijk, PO Box 444, 3300 AK Dordrecht, the Netherlands.

出版信息

Neth J Med. 2007 Nov;65(10):398-400.

Abstract

The diagnosis of disseminated intravascular coagulation (DIC) requires the presence of a fibrin-related marker. D-dimer is frequently used in clinical practice as a fibrin-related marker. We present a case of paraneoplastic DIC with a false-negative D-dimer test. Repeating the test using a different D-dimer assay as well as the measurement of other fibrinolysis markers confirmed the diagnosis of DIC.

摘要

弥散性血管内凝血(DIC)的诊断需要存在纤维蛋白相关标志物。D-二聚体在临床实践中经常作为纤维蛋白相关标志物使用。我们报告一例副肿瘤性DIC患者,其D-二聚体检测结果为假阴性。使用不同的D-二聚体检测方法重复检测以及检测其他纤溶标志物后确诊为DIC。

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