MacPherson Laura, Strong David R, Kahler Christopher W, Abrantes Ana M, Ramsey Susan E, Brown Richard A
Brown University Center for Alcohol and Addictions Studies, Providence, RI, USA.
Nicotine Tob Res. 2007 Dec;9(12):1297-307. doi: 10.1080/14622200701651734.
Little is known about how initial change following a smoking intervention relates to longer-term smoking outcomes among adolescent smokers with psychiatric comorbidity. The present study investigated this relationship among psychiatrically hospitalized adolescents (N = 183) who participated in a controlled trial comparing motivational interviewing to brief advice. Quit attempters (n = 37), reducers (n = 45), and maintainers (n = 101) were assembled based on, respectively, having made a quit attempt, having reduced smoking by at least 50%, and having reduced smoking by less than 50% in the first week after hospital discharge. Hierarchical linear models and generalized estimating equations were conducted to test group differences in average number of cigarettes per smoking day and odds of making a quit attempt during subsequent weeks of a 12-month continuous follow-up, and in cotinine-verified abstinence rates at 1, 6, and 12 months posthospitalization. Baseline smoking levels and presence of a substance use disorder or anxiety disorder were predictive of outcomes. After controlling for covariates, we found that quit attempters smoked less during follow-up than did the other change groups and that reducers smoked less than maintainers. Quit attempters evidenced a higher percentage of quit attempts during follow-up than did the other change groups. Reducers had a greater average percentage of quit attempts during follow-up than did maintainers. However, groups did not differ on cotinine-verified abstinence rates across the follow-up period. Findings have implications for initial post-treatment change as it relates to subsequent smoking and cessation outcomes among adolescent smokers at especially high risk for smoking persistence.
对于患有精神疾病合并症的青少年吸烟者而言,吸烟干预后的初始变化与长期吸烟结果之间的关系鲜为人知。本研究调查了参与一项对照试验(比较动机性访谈与简短建议)的精神科住院青少年(N = 183)之间的这种关系。根据分别在出院后第一周内进行过戒烟尝试、吸烟量减少至少50%以及吸烟量减少不到50%,将戒烟尝试者(n = 37)、减少吸烟者(n = 45)和维持吸烟者(n = 101)进行分组。采用分层线性模型和广义估计方程来检验在12个月连续随访的后续几周内,每天吸烟的平均数量、进行戒烟尝试的几率以及住院后1个月、6个月和12个月时经可替宁验证的戒烟率在各组之间的差异。基线吸烟水平以及物质使用障碍或焦虑症的存在可预测结果。在控制协变量后,我们发现戒烟尝试者在随访期间的吸烟量比其他变化组少,减少吸烟者的吸烟量比维持吸烟者少。戒烟尝试者在随访期间进行戒烟尝试的百分比高于其他变化组。减少吸烟者在随访期间进行戒烟尝试的平均百分比高于维持吸烟者。然而,在整个随访期间,各组经可替宁验证的戒烟率并无差异。这些发现对于治疗后的初始变化具有启示意义,因为它与吸烟持续风险特别高的青少年吸烟者随后的吸烟和戒烟结果相关。