输入蛋白α5缺陷小鼠的正常脑发育 - Suppr

Normal brain development in importin-alpha5 deficient-mice.

作者信息

Shmidt Tatjana, Hampich Franziska, Ridders Michael, Schultrich Stefanie, Hans Volkmar H, Tenner Katja, Vilianovich Larissa, Qadri Fatimunnisa, Alenina Natalia, Hartmann Enno, Köhler Matthias, Bader Michael

出版信息

Nat Cell Biol. 2007 Dec;9(12):1337-8; author reply 1339. doi: 10.1038/ncb1207-1337.

DOI:10.1038/ncb1207-1337

PMID:18059353

Abstract

摘要

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Normal brain development in importin-alpha5 deficient-mice.输入蛋白α5缺陷小鼠的正常脑发育

Nat Cell Biol. 2007 Dec;9(12):1337-8; author reply 1339. doi: 10.1038/ncb1207-1337.

A matter of some importins: nuclear transport factors in ES cell maintenance and differentiation.一些重要的问题：胚胎干细胞维持与分化中的核转运因子

Dev Cell. 2007 Feb;12(2):172-4. doi: 10.1016/j.devcel.2007.01.006.

Targeted disruption of one of the importin α family members leads to female functional incompetence in delivery.靶向破坏一个核输入蛋白家族成员会导致雌性在分娩时出现功能障碍。

FEBS J. 2011 May;278(9):1561-72. doi: 10.1111/j.1742-4658.2011.08079.x. Epub 2011 Mar 22.

Regional distribution of importin subtype mRNA expression in the nervous system: study of early postnatal and adult mouse.神经系统中输入蛋白亚型mRNA表达的区域分布：对出生后早期和成年小鼠的研究

Neuroscience. 2008 Dec 10;157(4):864-77. doi: 10.1016/j.neuroscience.2008.09.045. Epub 2008 Oct 2.

NF-kappaB p52, RelB and c-Rel are transported into the nucleus via a subset of importin alpha molecules.核因子-κB p52、RelB和c-Rel通过一部分输入蛋白α分子转运至细胞核。

Cell Signal. 2008 Aug;20(8):1442-51. doi: 10.1016/j.cellsig.2008.03.012. Epub 2008 Apr 1.

Developmental enhancement of alpha2-adrenoceptor-mediated suppression of inhibitory synaptic transmission onto mouse cerebellar Purkinje cells.α2肾上腺素能受体介导的对小鼠小脑浦肯野细胞抑制性突触传递抑制作用的发育增强

Neuroscience. 2008 Sep 22;156(1):143-54. doi: 10.1016/j.neuroscience.2008.07.018. Epub 2008 Jul 18.

Close homologue of adhesion molecule L1 promotes survival of Purkinje and granule cells and granule cell migration during murine cerebellar development.黏附分子L1的紧密同源物在小鼠小脑发育过程中促进浦肯野细胞和颗粒细胞的存活以及颗粒细胞迁移。

J Comp Neurol. 2009 Apr 10;513(5):496-510. doi: 10.1002/cne.21981.

Role of importin alpha8, a new member of the importin alpha family of nuclear transport proteins, in early embryonic development in cattle.输入蛋白α8（核转运蛋白输入蛋白α家族的新成员）在牛早期胚胎发育中的作用。

Biol Reprod. 2009 Aug;81(2):333-42. doi: 10.1095/biolreprod.109.077396. Epub 2009 May 6.

Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout mice.色氨酸羟化酶亚型在小鼠和人脑中的时空表达：来自Tph2基因敲除小鼠的一致数据

Eur Neuropsychopharmacol. 2009 Apr;19(4):266-82. doi: 10.1016/j.euroneuro.2008.12.005. Epub 2009 Feb 1.

Normal adult climbing fiber monoinnervation of cerebellar Purkinje cells in mice lacking MHC class I molecules.缺乏MHC I类分子的小鼠中，成年正常小鼠小脑浦肯野细胞的攀缘纤维单神经支配。

Dev Neurobiol. 2008 Jul;68(8):997-1006. doi: 10.1002/dneu.20639.

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A Kpna1-deficient psychotropic drug-induced schizophrenia model mouse for studying gene-environment interactions.用于研究基因-环境相互作用的 Kpna1 缺陷型精神分裂症模型小鼠。

Sci Rep. 2024 Feb 9;14(1):3376. doi: 10.1038/s41598-024-53237-3.

Activation of thousands of genes in the lungs and kidneys by sepsis is countered by the selective nuclear blockade.脓毒症激活肺部和肾脏中的数千个基因，被选择性核封锁所拮抗。

Front Immunol. 2023 Aug 11;14:1221102. doi: 10.3389/fimmu.2023.1221102. eCollection 2023.

Effects of Importin α1/KPNA1 deletion and adolescent social isolation stress on psychiatric disorder-associated behaviors in mice.Importin α1/KPNA1 缺失和青少年社交隔离应激对小鼠精神障碍相关行为的影响。

PLoS One. 2021 Nov 12;16(11):e0258364. doi: 10.1371/journal.pone.0258364. eCollection 2021.

Decoding inflammation, its causes, genomic responses, and emerging countermeasures.解码炎症、其病因、基因组反应及新兴对策。

Scand J Immunol. 2019 Dec;90(6):e12812. doi: 10.1111/sji.12812. Epub 2019 Aug 28.

Importin α5 Regulates Anxiety through MeCP2 and Sphingosine Kinase 1.Importin α5 通过 MeCP2 和鞘氨醇激酶 1 调节焦虑。

Cell Rep. 2018 Dec 11;25(11):3169-3179.e7. doi: 10.1016/j.celrep.2018.11.066.

Importin α: functions as a nuclear transport factor and beyond.importin α：作为核转运因子的功能及其他。

Proc Jpn Acad Ser B Phys Biol Sci. 2018;94(7):259-274. doi: 10.2183/pjab.94.018.

Importin-8 Modulates Division of Apical Progenitors, Dendritogenesis and Tangential Migration During Development of Mouse Cortex.输入蛋白8在小鼠皮质发育过程中调节顶端祖细胞的分裂、树突发生和切向迁移。

Front Mol Neurosci. 2018 Jul 10;11:234. doi: 10.3389/fnmol.2018.00234. eCollection 2018.

Importin α1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons.Importin α1 对于单纯疱疹病毒蛋白在成纤维细胞和神经元中的核输入以及衣壳组装是必需的。

PLoS Pathog. 2018 Jan 5;14(1):e1006823. doi: 10.1371/journal.ppat.1006823. eCollection 2018 Jan.

Genetic compensation: A phenomenon in search of mechanisms.基因补偿：一种尚待探寻作用机制的现象。

PLoS Genet. 2017 Jul 13;13(7):e1006780. doi: 10.1371/journal.pgen.1006780. eCollection 2017 Jul.

Karyopherin Alpha 1 Regulates Satellite Cell Proliferation and Survival by Modulating Nuclear Import.核转运蛋白α1通过调节核输入来调控卫星细胞的增殖与存活。

Stem Cells. 2016 Nov;34(11):2784-2797. doi: 10.1002/stem.2467. Epub 2016 Aug 1.

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Normal brain development in importin-alpha5 deficient-mice.

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