关于干细胞生态位的诸多热议。

Much HUBbub about stem-cell niches.

作者信息

Van Doren Mark

出版信息

Nat Cell Biol. 2007 Dec;9(12):1344-5. doi: 10.1038/ncb1207-1344.

Abstract

Stem cells, and the microenvironment or 'niche' that influences them, must often reside in a particular location within a tissue to perform their function. Integrin-mediated adhesion is now shown to regulate the location of the stem-cell niche in the Drosophila testis.

摘要

干细胞以及影响它们的微环境或“壁龛”，通常必须存在于组织内的特定位置才能发挥其功能。现已表明，整合素介导的黏附作用可调节果蝇睾丸中干细胞壁龛的位置。