van der Steeg A F W, De Vries J, Roukema J A
Department of Surgery, St Elisabeth Hospital, Tilburg, The Netherlands.
Eur J Surg Oncol. 2008 Nov;34(11):1225-30. doi: 10.1016/j.ejso.2007.10.009. Epub 2007 Dec 3.
Quality of life (QoL) in breast cancer survivors has become increasingly important. However, QoL is often assessed using a questionnaire meant to assess health status (HS). In this study the differences in outcomes between a HS and QoL questionnaire are shown and the correlation between both questionnaires is assessed.
From the 140 breast cancer survivors that participated in the study, 68 received breast conserving therapy (BCT) and 72 were treated with mastectomy (MTC). HS was measured using the RAND-36 and QoL was assessed with the WHOQOL-100. Scores were compared with healthy reference populations.
The scores on QoL in both treatment groups were comparable to those of healthy women. HS scores showed lower physical functioning and general health perceptions for the MTC women. Pearson correlations between both questionnaires ranged between 0.19 and 0.75. Thus, the results of both questionnaires were not interchangeable.
A HS questionnaire reflects functional impairments and reveals different areas of concern compared with a QoL questionnaire. The latter reflects the (dis)satisfaction of a patient and this seems not to mirror the functional limitations. Assessment of both objective functioning and subjective appraisal of functioning will result in treatment suggestions that meet the patients needs.
乳腺癌幸存者的生活质量(QoL)变得越来越重要。然而,生活质量通常使用旨在评估健康状况(HS)的问卷进行评估。在本研究中,展示了健康状况问卷和生活质量问卷在结果上的差异,并评估了这两种问卷之间的相关性。
在参与研究的140名乳腺癌幸存者中,68人接受了保乳治疗(BCT),72人接受了乳房切除术(MTC)。使用兰德36项健康调查简表测量健康状况,并用世界卫生组织生活质量测定量表100项(WHOQOL-100)评估生活质量。将得分与健康对照人群进行比较。
两个治疗组的生活质量得分与健康女性相当。乳房切除术组女性的健康状况得分在身体功能和总体健康感知方面较低。两种问卷之间的皮尔逊相关性在0.19至0.75之间。因此,两种问卷的结果不可互换。
与生活质量问卷相比,健康状况问卷反映了功能损害,并揭示了不同的关注领域。后者反映了患者的(不)满意度,而这似乎并未反映功能限制。对客观功能和功能主观评价的评估将产生符合患者需求的治疗建议。