Blandon Roberta E, Bharucha Adil E, Melton L Joseph, Schleck Cathy D, Babalola Ebenezer O, Zinsmeister Alan R, Gebhart John B
Department of Obstetrics and Gynecology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
Am J Obstet Gynecol. 2007 Dec;197(6):664.e1-7. doi: 10.1016/j.ajog.2007.08.064.
The objective of the study was to assess the incidence of and risk factors for pelvic floor repair (PFR) procedures after hysterectomy.
Using the Rochester Epidemiology Project database, we tracked the incidence of PFRs through June 2006 among 8220 Olmsted County, MN, women who had a hysterectomy for benign indications between 1965 and 2002.
The cumulative incidence of PFR after hysterectomy was 5.1% by 30 years. This risk was not influenced by age at hysterectomy or calendar period. Future PFR was more frequently required in women who had prolapse, whether they underwent a hysterectomy alone (eg, vaginal [hazard ratio (HR) 4.3; 95% confidence interval (CI) 2.5 to 7.3], abdominal [HR 3.9; 95% CI 1.9 to 8.0]) or a hysterectomy and PFR (ie, vaginal [HR 1.9; 95% CI 1.3 to 2.7] or abdominal [HR 2.9; 95% CI 1.5 to 5.5]).
Compared with women without prolapse, women who had a hysterectomy for prolapse were at increased risk for subsequent PFR.
本研究的目的是评估子宫切除术后盆底修复（PFR）手术的发生率及危险因素。
利用罗切斯特流行病学项目数据库，我们追踪了明尼苏达州奥姆斯特德县8220名在1965年至2002年间因良性指征行子宫切除术的女性至2006年6月的PFR发生率。
子宫切除术后30年PFR的累积发生率为5.1%。该风险不受子宫切除时年龄或时间的影响。有子宫脱垂的女性更常需要进行后续PFR，无论她们是单纯接受子宫切除术（如经阴道[风险比（HR）4.3；95%置信区间（CI）2.5至7.3]、经腹[HR 3.9；95% CI 1.9至8.0]）还是子宫切除术加PFR（即经阴道[HR 1.9；95% CI 1.3至2.7]或经腹[HR 2.9；95% CI 1.5至5.5]）。
与无子宫脱垂的女性相比，因子宫脱垂行子宫切除术的女性后续发生PFR的风险增加。
