[Isoprenoide pathway and cell proliferation in the yeast Saccharomyces cerevisiae].
作者信息
Blanchard L, Chambon C, Marcireau C, Karst F
机构信息
Laboratoire de Biochimie et Génétique des Microorganismes, Université de Poitiers, France.
出版信息
C R Seances Soc Biol Fil. 1991;185(5):312-8.
PMID:1806190
Abstract
Yeast mutants blocked in farnesyl diphosphate (FPP) synthetase have been isolated. Their specific phenotype is likely linked to a lowering in the FPP pool required for protein prenylation. The structural gene of FPP synthetase has been isolated. Complete inactivation of FPP synthetase by gene disruption is letal for the yeast cells.
摘要
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