van Zuuren E J, Boer F, Lai a Fat E J S, Terreehorst I
Leids Universitair Medisch Centrum, polikliniek Huidziekten, BI-Q, Postbus 9600, 2300 RC Leiden.
Ned Tijdschr Geneeskd. 2007 Nov 10;151(45):2531-4.
Three men of 65, 41 and 54 years old respectively, developed an anaphylactic reaction during a medical procedure. Two were under general anaesthesia and the third was undergoing urinary catheterisation. After allergy tests chlorhexidine, an ingredient in the gel which was used during the urinary catheterisation procedure, was found to be the causative agent in all three men. Following treatment the clinical course was good. Chlorhexidine is a widely used antiseptic and disinfectant. Despite multiple publications on anaphylactic reactions mostly during surgery under general anaesthesia or urological procedures, chlorhexidine is often initially overlooked as a cause of anaphylaxis. All three men had had previous reactions to chlorhexidine, however, not enough attention was paid to this fact, or it was not thought of.
三名分别为65岁、41岁和54岁的男性在医疗过程中发生了过敏反应。其中两人处于全身麻醉状态，第三人正在接受导尿术。经过过敏测试，发现导尿术过程中使用的凝胶中的一种成分洗必泰是这三名男性过敏反应的致病因素。经过治疗，临床过程良好。洗必泰是一种广泛使用的防腐剂和消毒剂。尽管有大量关于过敏反应的出版物，主要是在全身麻醉手术或泌尿外科手术期间，但洗必泰常常最初被忽视是过敏反应的原因。然而，这三名男性之前都对洗必泰有过反应，但这一事实没有得到足够的重视，或者根本没有被考虑到。
