Misíková Z, Kost'álová L, Beno P, Pasková M, Lescisinová M, Kúseková M, Lukác P, Benacková H
II. detská klinika, Detská fakultná nemocnica, Bratislava.
Cesk Pediatr. 1991 Dec;46(12):531-3.
The authors give an account of 71 patients treated on account of complete growth hormone deficiency in Slovakia. Before the age of five the diagnosis was established in 24 children, after the age of 10 in 17 patients. Nine patients suffer from panhypopituitarism, while isolated deficiency of growth hormone was recorded in 34 patients. Perinatal pathology plays an important role in the aetiology. A tumour caused the disorder in five children. Treatment of the majority of patients was not systematic and was inadequate because of shortage of growth hormone. When regular substitution treatment was started before the age of 8 years, the therapeutic results were very satisfactory. The authors draw attention to the danger of further deterioration of care of children with growth hormone deficiency for economic reasons.
作者介绍了斯洛伐克71例因完全性生长激素缺乏症接受治疗的患者情况。5岁前确诊的有24名儿童,10岁后确诊的有17名患者。9名患者患有全垂体功能减退症,34名患者记录为单纯生长激素缺乏。围产期病理在病因学中起重要作用。肿瘤导致5名儿童出现该病症。由于生长激素短缺,大多数患者的治疗不系统且不充分。8岁前开始规律替代治疗时,治疗效果非常令人满意。作者提请注意,由于经济原因,生长激素缺乏症儿童的护理可能会进一步恶化。