• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

溶组织内阿米巴基因组的结构与内容。

Structure and content of the Entamoeba histolytica genome.

作者信息

Clark C G, Alsmark U C M, Tazreiter M, Saito-Nakano Y, Ali V, Marion S, Weber C, Mukherjee C, Bruchhaus I, Tannich E, Leippe M, Sicheritz-Ponten T, Foster P G, Samuelson J, Noël C J, Hirt R P, Embley T M, Gilchrist C A, Mann B J, Singh U, Ackers J P, Bhattacharya S, Bhattacharya A, Lohia A, Guillén N, Duchêne M, Nozaki T, Hall N

机构信息

Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.

出版信息

Adv Parasitol. 2007;65:51-190. doi: 10.1016/S0065-308X(07)65002-7.

DOI:10.1016/S0065-308X(07)65002-7
PMID:18063096
Abstract

The intestinal parasite Entamoeba histolytica is one of the first protists for which a draft genome sequence has been published. Although the genome is still incomplete, it is unlikely that many genes are missing from the list of those already identified. In this chapter we summarise the features of the genome as they are currently understood and provide previously unpublished analyses of many of the genes.

摘要

肠道寄生虫溶组织内阿米巴是最早公布基因组草图序列的原生生物之一。尽管基因组仍不完整,但已识别的基因列表中不太可能遗漏许多基因。在本章中,我们总结了目前所了解的基因组特征,并提供了许多基因此前未发表的分析。

相似文献

1
Structure and content of the Entamoeba histolytica genome.溶组织内阿米巴基因组的结构与内容。
Adv Parasitol. 2007;65:51-190. doi: 10.1016/S0065-308X(07)65002-7.
2
Unique organisation of tRNA genes in Entamoeba histolytica.溶组织内阿米巴tRNA基因的独特组织方式。
Mol Biochem Parasitol. 2006 Mar;146(1):24-9. doi: 10.1016/j.molbiopara.2005.10.013. Epub 2005 Oct 28.
3
Identification of developmentally regulated genes in Entamoeba histolytica: insights into mechanisms of stage conversion in a protozoan parasite.溶组织内阿米巴中发育调控基因的鉴定:对原生动物寄生虫阶段转换机制的见解。
Cell Microbiol. 2007 Jun;9(6):1426-44. doi: 10.1111/j.1462-5822.2006.00882.x. Epub 2007 Jan 22.
4
Comparative genomics of Dictyostelium discoideum and Entamoeba histolytica.盘基网柄菌与溶组织内阿米巴的比较基因组学
Curr Opin Microbiol. 2005 Oct;8(5):606-11. doi: 10.1016/j.mib.2005.08.009.
5
The secretory pathway of Entamoeba histolytica: characterization and expression of the SRP54 gene.
Arch Med Res. 1997;28 Spec No:56-8.
6
The secretory pathway of Entamoeba histolytica: characterization and expression of the ERD2 gene.溶组织内阿米巴的分泌途径:ERD2基因的表征与表达
Arch Med Res. 1997;28 Spec No:59-61.
7
Organization of Entamoeba histolytica ribosomal and structural genes in PFGE.变形虫核糖体和结构基因在脉冲场凝胶电泳中的组织情况
Arch Med Res. 1997;28 Spec No:8-10.
8
Genome re-duplication and irregular segregation occur during the cell cycle of Entamoeba histolytica.
Biosci Rep. 2007 Dec;27(6):373-84. doi: 10.1007/s10540-007-9058-8.
9
Three conserved cis-acting sequences in the core promoter control gene expression in the protozoan parasite Entamoeba histolytica.
Arch Med Res. 1997;28 Spec No:41-2.
10
Identification of genomic responses to collagen binding by trophozoites of Entamoeba histolytica.溶组织内阿米巴滋养体对胶原蛋白结合的基因组反应鉴定。
J Infect Dis. 2004 Aug 1;190(3):448-57. doi: 10.1086/422323. Epub 2004 Jul 2.

引用本文的文献

1
The history of entamoebiasis.肠阿米巴病的历史。
Parasitology. 2025 May;152(6):563-572. doi: 10.1017/S0031182025100279.
2
Identification and characterization of archaeal-type FAD synthase as a novel tractable drug target from the parasitic protozoa .鉴定和表征古菌型 FAD 合酶作为寄生原生动物的新型可处理药物靶点。
mSphere. 2024 Sep 25;9(9):e0034724. doi: 10.1128/msphere.00347-24. Epub 2024 Aug 27.
3
Characterization of Entamoeba fatty acid elongases; validation as targets and provision of promising leads for new drugs against amebiasis.
肠贾第鞭毛虫脂肪酸延长酶的特性;作为靶标验证和提供针对阿米巴病的新药有希望的先导化合物。
PLoS Pathog. 2024 Aug 22;20(8):e1012435. doi: 10.1371/journal.ppat.1012435. eCollection 2024 Aug.
4
Glycerol biosynthetic pathway plays an essential role in proliferation and antioxidative defense in the human enteric protozoan parasite Entamoeba histolytica.甘油生物合成途径在人类肠道原生动物寄生虫溶组织内阿米巴的增殖和抗氧化防御中起着至关重要的作用。
Sci Rep. 2023 Sep 5;13(1):14596. doi: 10.1038/s41598-023-40670-z.
5
Extracellular Cysteine Proteases of Key Intestinal Protozoan Pathogens-Factors Linked to Virulence and Pathogenicity.肠道原虫关键病原体细胞外半胱氨酸蛋白酶-与毒力和致病性相关的因素。
Int J Mol Sci. 2023 Aug 16;24(16):12850. doi: 10.3390/ijms241612850.
6
Unique features of glycerophospholipid metabolism; has the . lipid metabolism network evolved through gene loss and gain to enable parasitic life cycle adaptation?甘油磷脂代谢的独特特征;脂质代谢网络是否通过基因的丢失和获得进化而来,以适应寄生生命周期?
mSphere. 2023 Oct 24;8(5):e0017423. doi: 10.1128/msphere.00174-23. Epub 2023 Aug 16.
7
Glycogen Metabolism and Its Role in Growth and Encystation in .糖原代谢及其在……生长和包囊形成中的作用
Life (Basel). 2023 Jul 8;13(7):1529. doi: 10.3390/life13071529.
8
Amoebiasis: Advances in Diagnosis, Treatment, Immunology Features and the Interaction with the Intestinal Ecosystem.阿米巴病:诊断、治疗、免疫学特征的进展及与肠道生态系统的相互作用。
Int J Mol Sci. 2023 Jul 21;24(14):11755. doi: 10.3390/ijms241411755.
9
The Role of Acetate Kinase in the Human Parasite .乙酸激酶在人体寄生虫中的作用
Parasitologia. 2022 Jun;2(2):147-159. doi: 10.3390/parasitologia2020014. Epub 2022 Jun 16.
10
Pathogenicity and virulence of , the agent of amoebiasis.致病力与毒力的 ,阿米巴病的病原体。
Virulence. 2023 Dec;14(1):2158656. doi: 10.1080/21505594.2022.2158656.