Nathanielsz Peter W, Poston Lucilla, Taylor Paul D
Department of Obstetrics and Gynecology, Center for Pregnancy and Newborn Research, The University of Texas of Health Science Center, 7703 Floyd Curl Drive, MSC 7836, San Antonio, TX 78229, USA.
Clin Perinatol. 2007 Dec;34(4):515-26, v. doi: 10.1016/j.clp.2007.09.005.
The developed and developing worlds are experiencing an epidemic of obesity and associated predisposition to diabetes. This epidemic places a major drain on health care resources. It is now clear that maternal obesity and gestational diabetes have major adverse effects on the developing fetus that lead to increased neonatal morbidity and mortality, as discussed elsewhere in this issue. Obesity in pregnancy and gestational diabetes represent a special problem, not only as a result of their immediate adverse effects on maternal health and pregnancy outcome, but also because of growing evidence for their persistent and deleterious effects on the developing child.
发达国家和发展中国家都在经历肥胖流行以及随之而来的糖尿病易感性增加的问题。这一流行病给医疗资源带来了巨大消耗。现在很清楚，正如本期其他地方所讨论的，孕产妇肥胖和妊娠期糖尿病对发育中的胎儿有重大不良影响，会导致新生儿发病率和死亡率增加。孕期肥胖和妊娠期糖尿病是一个特殊问题，不仅因为它们对孕产妇健康和妊娠结局有直接不良影响，还因为越来越多的证据表明它们对发育中的儿童有持续的有害影响。
