Kluivers Kirsten B, Johnson Neil P, Chien Patrick, Vierhout Mark E, Bongers Marliesy, Mol Ben W J
Radboud University Nijmegen Medical Centre, Department of Obstetrics and Gynaecology, Nijmegen, The Netherlands.
Eur J Obstet Gynecol Reprod Biol. 2008 Jan;136(1):3-8. doi: 10.1016/j.ejogrb.2007.06.004. Epub 2007 Dec 11.
The objective of this study was to investigate the randomized studies reporting on quality of life after laparoscopic hysterectomy as compared to abdominal hysterectomy. A systematic qualitative review was performed on published studies identified by the databases PubMed and EMBASE, as well as cross-references. Randomized clinical trials on laparoscopic versus abdominal hysterectomy were assessed for the methods in which studies reported on postoperative health or quality of life as an outcome measure. Study results were described qualitatively. Thirty papers, published between 1994 and 2004, were identified. Only seven studies, incorporating data on 1450 patients, reported on postoperative health or quality of life. Four of these studies used eight different validated quality of life questionnaires. Two of these four studies reported significant differences between the treatment groups, with better quality of life in the first 6 weeks after laparoscopic hysterectomy when compared to the abdominal approach. Although, the main reason for performing a laparoscopic hysterectomy instead of an abdominal hysterectomy is the improvement of quality of life, only a few studies have used this as an outcome measure. The data available show that laparoscopic hysterectomy performs equally or better in terms of postoperative health and quality of life in the first weeks after surgery. In the decision for an approach to hysterectomy, the advantage of better quality of life should be offset against the increased risk of complications in laparoscopic hysterectomy.
本研究的目的是调查与经腹子宫切除术相比,关于腹腔镜子宫切除术后生活质量的随机研究。对通过数据库PubMed和EMBASE以及交叉引用确定的已发表研究进行了系统的定性综述。评估了关于腹腔镜与经腹子宫切除术的随机临床试验中,研究报告术后健康或生活质量作为结局指标的方法。对研究结果进行了定性描述。共识别出1994年至2004年间发表的30篇论文。只有7项纳入了1450例患者数据的研究报告了术后健康或生活质量。其中4项研究使用了8种不同的经过验证的生活质量问卷。这4项研究中有2项报告了治疗组之间的显著差异,与经腹手术相比,腹腔镜子宫切除术后前6周的生活质量更好。尽管进行腹腔镜子宫切除术而非经腹子宫切除术的主要原因是生活质量的改善,但只有少数研究将其用作结局指标。现有数据表明,在术后最初几周,腹腔镜子宫切除术在术后健康和生活质量方面表现相同或更好。在决定子宫切除手术方式时,生活质量更好的优势应与腹腔镜子宫切除术并发症风险增加相权衡。