Chiaretto Giuseppina, Zavagnin Paola, Bettini Francesca, Mancin Marzia, Minorello Claudio, Saccardin Cristina, Ricci Antonia
National Reference Laboratory for Salmonella, Istituto Zooprofilattico delle Venezie, Viale dell'Università 10, 35020 Legnaro (Padova), Italy.
Vet Microbiol. 2008 Apr 30;128(3-4):406-13. doi: 10.1016/j.vetmic.2007.10.016. Epub 2007 Oct 22.
Salmonella strains isolated from poultry and poultry products over the period 2005-2006 have been investigated in order to ascertain the presence of extended spectrum cephalosporins (ESC) resistance. Twelve (ESC)-resistant isolates (n=1 S. Enteritidis, n=1 S. Braenderup and n=10 S. Livingstone) were characterized as SHV-12-positive. The multi-drug resistant S. Livingstone SHV-12-producing isolates, untypeable by pulsed-field gel electrophoresis (PFGE), showed a clonal relationship by random amplified polymorphic DNA (RAPD) analysis. The SHV-12 beta-lactamase is reported for the first time in Salmonella enterica strains isolated from poultry in Italy. The results suggest poultry as a source of Salmonella carrying extended spectrum beta-lactamases (ESBLs) genes and highlights the need of monitoring animal productions to prevent spreading of (ESC)-resistant strains.
为确定超广谱头孢菌素（ESC）耐药性的存在情况，对2005年至2006年期间从家禽及家禽产品中分离出的沙门氏菌菌株进行了调查。12株（ESC）耐药菌株（1株肠炎沙门氏菌、1株布伦德拉普沙门氏菌和10株利文斯通沙门氏菌）被鉴定为SHV-12阳性。通过脉冲场凝胶电泳（PFGE）无法分型的产SHV-12的多重耐药利文斯通沙门氏菌分离株，经随机扩增多态性DNA（RAPD）分析显示存在克隆关系。在意大利从家禽中分离出的肠炎沙门氏菌菌株中首次报道了SHV-12β-内酰胺酶。结果表明家禽是携带超广谱β-内酰胺酶（ESBLs）基因的沙门氏菌的来源，并强调了监测动物生产以防止（ESC）耐药菌株传播的必要性。
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