[Olfactory neuroblastoma--a report of 4 cases and review of literature].

This paper reports 4 patients with pathologically proven olfactory neuroblastoma. This tumor most commonly occurs along the medial line of the nasal cavity, base of the anterior cranial fossa, or the ethmoid sinuses. Special stain or electron-microscopy should be done routinely to ensure diagnostic accuracy if a mass at the above sites was suspected to be an olfactory neuroblastoma. Ample excision and preoperative and/or postoperative radiotherapy was recommended. The irradiation field should be large enough and the dose more than 60 Gy. The prognosis of patients in Group C of Kadish classification and children was poor. Recurrence and metastasis might still occur many years after the initial treatment, necessitating close follow-up.