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采用高效液相色谱法测定药物制剂中西咪替丁及相关杂质。

Determination of cimetidine and related impurities in pharmaceutical formulations by high-performance liquid chromatography.

作者信息

Betto P, Ciranni-Signoretti E, Di Fava R

机构信息

Istituto Superiore di Sanità, Rome, Italy.

出版信息

J Chromatogr. 1991 Nov 8;586(1):149-52. doi: 10.1016/0021-9673(91)80033-d.

DOI:10.1016/0021-9673(91)80033-d
PMID:1806550
Abstract

The analytical characteristics of cimetidine tablets were studied. A high-performance liquid chromatographic method was developed in order to assay cimetidine and its related impurities simultaneously. A reversed-phase system and diode-array detector were used.

摘要

对西咪替丁片的分析特性进行了研究。开发了一种高效液相色谱法，以便同时测定西咪替丁及其相关杂质。使用了反相系统和二极管阵列检测器。

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