Guan You-yan, Li Ning-chen, Zhou Li-qun, He Zhi-song, Li Ming, Na Yan-qun
Department of Urology, First Hospital, Peking University, Beijing 100034, China.
Zhonghua Wai Ke Za Zhi. 2007 Sep 15;45(18):1260-3.
To evaluate the prognostic factors of ureter transitional cell carcinoma (TCC).
Between January 2001 and December 2005 133 TCC patients were treated. And the data was retrospectively analyzed.
A mean age of the 133 patients was 68 years (range 43 - 87 years) at diagnosis. Altogether the non-invasive ureter TCC was found in 42 patients (31.6%) and the invasive ureter TCC in 91 patients (68.4%). Invasive ureter TCC growth was more common in distally located tumors (82.5%) compared to mid (62.5%) and proximal ureter (47.1%). Tumor stage, grade and location of the tumor were all correlated with disease specific survival in a univariate analysis. In a multivariate Cox analysis, tumor stage and grade were significantly associated with disease specific survival.
More invasive tumors are found in ureter than in bladder. Ureter cancer is more frequently found in the distal part. Distally located ureteral tumors are more likely invading into the muscular cell layers compared to proximally located tumors. Tumor stage and grade are still the more important prognostic factors for ureter TCC.
评估输尿管移行细胞癌（TCC）的预后因素。
2001年1月至2005年12月期间，对133例TCC患者进行了治疗，并对数据进行回顾性分析。
133例患者诊断时的平均年龄为68岁（范围43 - 87岁）。共发现42例（31.6%）非侵袭性输尿管TCC和91例（68.4%）侵袭性输尿管TCC。与输尿管中段（62.5%）和上段（47.1%）肿瘤相比，侵袭性输尿管TCC生长在远端肿瘤中更为常见（82.5%）。在单因素分析中，肿瘤分期、分级和肿瘤位置均与疾病特异性生存相关。在多因素Cox分析中，肿瘤分期和分级与疾病特异性生存显著相关。
输尿管中发现的侵袭性肿瘤比膀胱中更多。输尿管癌更常见于远端。与近端肿瘤相比，远端输尿管肿瘤更有可能侵犯肌层。肿瘤分期和分级仍然是输尿管TCC更重要的预后因素。
