Ozaki Shuji
Division of Transfusion Medicine and Hematology, Tokushima University Hospital.
Nihon Rinsho. 2007 Dec;65(12):2261-7.
Multiple myeloma is an incurable malignancy characterized by the accumulation of neoplastic plasma cells in the bone marrow and osteolytic bone destruction. The imaging techniques play an essential role in the assessment of skeletal involvement, the detection of extramedullary diseases, and the characterization of organ complications. Plain X-rays are routinely used for skeletal surveys; however, the sensitivity is not sufficient to detect early osteolytic lesions. New imaging techniques such as multislice computed tomography (CT), magnetic resonance imaging (MRI), and whole body positron emission tomography (PET) offer advanced diagnostic accuracy. These imaging modalities allow for more precise staging and contribute to further improvement in the management of this disease.
多发性骨髓瘤是一种无法治愈的恶性肿瘤，其特征是肿瘤性浆细胞在骨髓中积聚并导致溶骨性骨破坏。成像技术在评估骨骼受累情况、检测髓外疾病以及确定器官并发症特征方面发挥着重要作用。普通X线通常用于骨骼检查；然而，其敏感性不足以检测早期溶骨性病变。多层计算机断层扫描（CT）、磁共振成像（MRI）和全身正电子发射断层扫描（PET）等新的成像技术提供了更高的诊断准确性。这些成像方式能够实现更精确的分期，并有助于进一步改善该疾病的治疗管理。
