Cao Bing-Yan, Mi Jie, Gong Chun-Xiu, Cheng Hong, Yan Chun, Hou Dong-Qing, Liu Min, Sang Yan-Mei, Zhu Cheng
Beijing Children's Hospital, Capital Medical University, Beijing 100045, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2007 Jul;28(7):631-4.
To study the prevalence of Diabetes mellitus (DM) in children and adolescents and to describe the characteristics on age, gender and district distribution of schoolchildren, in Beijing.
A cross-sectional screening program the fasting capillary blood glucose (FCBG) was carried out in 19,593 schoolchildren in 7 areas of Beijing from March to October, 2004. According to the WHO diagnostic criteria: DM was set as FCBG < or = 6.1 mmol/L, impaired fasting glucose (IFG) was set as 5.6 mmol/L < or = FCBG < 6.1 mmol/L.
The total aggregate age-adjusted prevalence rates of DM and IFG were 5.7 per thousand and 13.5 per thousand, respectively. The prevalence rates of DM and IFG in males were significantly higher than that in females (7.7 per thousand vs. 3.6 per thousand and 26.8 per thousand vs. 11.3 per thousand. DM X2 = 12.27, P = 0.0005; IFG X2 =47.29, P = 0.0000). Among seven districts, East District had the highest prevalence rates of DM and IFG, 8.9 per thousand and 27.4 per thousand (companied high obesity 28.68%) while Ping-Gu District having the lowest ones as 2.0 per thousand and 7.5 per thousand (obese 12.75%) respectively (X2 = 13.75, and X2 = 32.65, P = 0.0002 and P < 0.0001). The DM prevalence rates between districts ranged from 2.0 per thousand to 8.9 per thousand, X2 = 18.94, P = 0.004 and the IFG prevalence of districts ranged from 7.5 per thousand to 27.4 per thousand (X2 = 52.05, P < 0.0001). The prevalence rates of DM among different age groups increased with age, with the highest prevalence of IFG on the 10-14 age group. Among boys, the highest prevalence rates of DM and IFG fell in the 15-18 and 10-14 age groups respectively while the highest prevalence rates on both DM and IFG among girls were in the same age group 10-14.
The high prevalence rates on DM and IFG were seen in Beijing and showed significant discrimination on age, gender and district distribution. More developed urban district and males had a higher prevalence, companied by higher obesity prevalence. Age seemed to be a high risk factor on DM for boys while the puberty development seemed a high risk factor for girls.
研究北京儿童及青少年糖尿病(DM)的患病率,并描述在校学生的年龄、性别及地区分布特征。
2004年3月至10月,对北京7个地区的19593名在校学生开展了空腹毛细血管血糖(FCBG)横断面筛查项目。根据世界卫生组织诊断标准:DM定义为FCBG≤6.1mmol/L,空腹血糖受损(IFG)定义为5.6mmol/L≤FCBG<6.1mmol/L。
DM和IFG的年龄调整后总患病率分别为千分之5.7和千分之13.5。男性DM和IFG的患病率显著高于女性(分别为千分之7.7对千分之3.6以及千分之26.8对千分之11.3。DM:X²=12.27,P=0.0005;IFG:X²=47.29,P=0.0000)。在7个区中,东城区DM和IFG的患病率最高,分别为千分之8.9和千分之27.4(伴有高肥胖率28.68%),而平谷区最低,分别为千分之2.0和千分之7.5(肥胖率12.75%)(X²=13.75和X²=32.65,P=0.0002和P<0.0001)。各区DM患病率在千分之2.0至千分之8.9之间(X²=18.94,P=0.004),IFG患病率在千分之7.5至千分之27.4之间(X²=52.05,P<0.0001)。不同年龄组的DM患病率随年龄增长而升高,IFG患病率在10-14岁年龄组最高。在男孩中,DM和IFG的患病率最高分别在15-18岁和10-14岁年龄组,而女孩中DM和IFG的患病率最高均在10-14岁同一年龄组。
北京DM和IFG患病率较高,且在年龄、性别及地区分布上存在显著差异。城市较发达地区及男性患病率较高,且伴有较高的肥胖率。年龄似乎是男孩患DM的高风险因素,而青春期发育似乎是女孩患DM的高风险因素。