在离体犬耳动脉中，酪胺可引起强烈的血管收缩，但尼古丁无明显收缩作用。
Potent vasoconstriction by tyramine but no significant constriction by nicotine in isolated dog ear arteries.
作者信息
Chiba S, Tsukada M
机构信息
Department of Pharmacology, Shinshu University School of Medicine, Matsumoto.
出版信息
Tohoku J Exp Med. 1991 Nov;165(3):239-41.
PMID:1807012
Abstract
Using the cannula inserted method, vascular effects of nicotine were investigated in isolated, perfused dog intermediate auricular arteries, comparing with those of norepinephrine and tyramine. Norepinephrine and tyramine produced strong vasoconstrictions in a dose-related manner, but nicotine did not induce any significant vasoconstriction.
摘要
采用套管插入法，在离体灌注的犬心耳中间动脉中研究了尼古丁的血管效应，并与去甲肾上腺素和酪胺的血管效应进行了比较。去甲肾上腺素和酪胺以剂量相关的方式产生强烈的血管收缩，但尼古丁未引起任何显著的血管收缩。
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