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临床遗传学中的精神疾病II:个体化复发风险。

Psychiatric disorders in clinical genetics II: Individualizing recurrence risks.

作者信息

Austin Jehannine C, Palmer Christina G S, Rosen-Sheidley Beth, Veach Patricia McCarthy, Gettig Elizabeth, Peay Holly L

机构信息

Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada,

出版信息

J Genet Couns. 2008 Feb;17(1):18-29. doi: 10.1007/s10897-007-9121-4. Epub 2007 Dec 11.

Abstract

This is the second article of a two-part professional development series on genetic counseling for personal and family histories of psychiatric disorders. It is based on an Educational Breakout Session presented by The Psychiatric Special Interest Group of the National Society of Genetic Counselors at the 2006 Annual Education Conference. While the first article in this two part series dealt with addressing family histories of psychiatric disorders in clinical practice, the following discussion deals with the generation and provision of individualized recurrence risks for psychiatric disorders, based on empiric risk data. We present four cases that illustrate important components of and process for generating individualized risk assessment for family histories of psychiatric disorders.

摘要

这是关于精神疾病个人和家族病史的遗传咨询专业发展系列文章的第二篇。它基于美国国家遗传咨询师协会精神科特别兴趣小组在2006年年度教育会议上举办的一次教育分组会议。虽然这个系列文章的第一篇讨论了在临床实践中处理精神疾病家族病史的问题,但以下讨论基于经验风险数据,涉及精神疾病个体化复发风险的生成和提供。我们展示了四个案例,这些案例说明了为精神疾病家族病史生成个体化风险评估的重要组成部分和过程。

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