Tunn P-U, Fehlberg S, Andreou D, Kettelhack C
Klinik für Chirurgie und Chirurgische Onkologie, Universitätsmedizin Berlin, Charité Campus Buch, HELIOS Klinikum Berlin-Buch.
Z Orthop Unfall. 2007 Nov-Dec;145(6):753-9. doi: 10.1055/s-2007-965757.
Limb salvage procedures in cases of bone tumours of the pelvis are established. In this retrospective study the clinical results after implantation of megaprostheses of the pelvis are reported.
Between November 1994 and September 2004 an endoprosthetic replacement of the pelvis was performed in 24 consecutive patients, fourteen females and ten males. The mean age was 49.3 years (range: 17-64 years). In ten cases a complete and in fourteen an incomplete internal hemipelvectomy was done. Thirteen patients presented with a primary bone tumour and eleven with a bone metastasis. The tumour volume ranged between 50 and 1315 ml (median: 352 ml). The mean follow-up was 98 months.
In 23 of the 24 patients an R0 resection was achieved. Local recurrences were observed in five patients (20.8%). Deep infections developed in ten patients (41.7%) postoperatively. In two of these ten patients a secondary external hemipelvectomy was necessary. Eight patients (33.3%) developed a paralysis of the femoral and/or sciatic nerve, and a loosening of the endoprosthesis was observed in four cases (16.7%). Two patients died within 30 days postoperatively (pulmonary embolism, dissection of the abdominal aorta). Eight of the 24 patients are still alive, two of them after secondary hemipelvectomy and another after removal of the endoprosthesis due to infection. The functional results of the five surviving patients with an endoprosthesis, according to the MSTS scoring system, are good in two and poor in three patients.
Internal hemipelvectomy and reconstruction of the pelvic girdle with endoprostheses is associated with a high rate of complications. Each single case should be critically evaluated and alternative procedures should be considered.
骨盆骨肿瘤的保肢手术已确立。本回顾性研究报告了骨盆巨型假体植入后的临床结果。
1994年11月至2004年9月,连续24例患者接受了骨盆内假体置换术,其中女性14例,男性10例。平均年龄为49.3岁(范围:17 - 64岁)。10例患者进行了完全性、14例患者进行了不完全性半骨盆切除术。13例患者为原发性骨肿瘤,11例患者为骨转移瘤。肿瘤体积在50至1315毫升之间(中位数:352毫升)。平均随访时间为98个月。
24例患者中有23例实现了R0切除。5例患者(20.8%)出现局部复发。10例患者(41.7%)术后发生深部感染。这10例患者中有2例需要进行二期半骨盆切除术。8例患者(33.3%)出现股神经和/或坐骨神经麻痹,4例患者(16.7%)观察到假体松动。2例患者术后30天内死亡(肺栓塞、腹主动脉夹层)。24例患者中有8例仍然存活,其中2例在二期半骨盆切除术后存活,另1例因感染取出假体后存活。根据MSTS评分系统,5例存活的假体患者中,2例功能结果良好,3例较差。
半骨盆切除术及骨盆带假体重建并发症发生率较高。应严格评估每一个病例,并考虑替代手术方法。