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定制设计和 3D 打印钛髋臼植入物用于肿瘤切除后的髋臼重建。

Custom designed and 3D-printed titanium pelvic implants for acetabular reconstruction after tumour resection.

机构信息

Leiden University Medical Centre, Leiden, The Netherlands.

Department of Orthopaedic Surgery, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.

出版信息

Hip Int. 2023 Sep;33(5):905-915. doi: 10.1177/11207000221135068. Epub 2022 Nov 21.

Abstract

BACKGROUND

Reconstructive procedure following resection of large pelvic tumours around the hip joint remains a complex challenge.

METHODS

This study presents a retrospective case series of patients presenting with benign or malignant pelvic tumour for which an internal hemipelvectomy including the hip joint and subsequent reconstruction with a custom designed 3-dimensional printed titanium pelvic implant (3DPPI) has been performed between August 2013 and January 2018.

RESULTS

15 consecutive patients with a median age of 33.9 years (IQR 26.4-72.2) and a median BMI of 20.7 kg/m (IQR 19.0-33.3) were reviewed after median follow-up of 33.8 months (IQR 24.0-78.1). The majority of patients presented with a malignant tumour as their principal diagnosis (  13, 86.7%). The median surgical time was 5.5 hours (IQR 4.5-8.5) and median peri-operative blood loss was 5000 ml (IQR 2000-10000). The median MSTS score at follow-up was 63.3% (IQR 51.7-86.7%). The median NRS in rest was 0.0 (IQR 0.0-5.0), the median NRS during activity was 2.0 (IQR 0.5-7.0) and the median HOOS-PS was 76.6% (IQR 67.9-91.0). 4 patients had implant-specific complications (  4, 26.6%); 1 hip dislocation (Henderson type 1a), 3 structural complications (type 3a), 1 deep infection (type 4a) and 1 local tumour recurrence (type 5b). At follow-up, 4 out of 15 implants were classified as a failure, resulting in an implant survival rate of 73.3%.

CONCLUSIONS

Acceptable peri-operative outcomes, functional results, complication rates and short-term implant survival can be achieved in a cohort of complex patients undergoing 3DPPI reconstruction after hemipelvectomy including the acetabulum.

摘要

背景

髋关节周围大型骨盆肿瘤切除后的重建仍然是一个复杂的挑战。

方法

本研究回顾性分析了 2013 年 8 月至 2018 年 1 月期间接受髋关节内半骨盆切除术和随后使用定制设计的 3 维打印钛骨盆植入物(3DPPI)重建的良性或恶性骨盆肿瘤患者的病例系列。

结果

15 例连续患者的中位年龄为 33.9 岁(IQR 26.4-72.2),BMI 中位数为 20.7kg/m(IQR 19.0-33.3),中位随访 33.8 个月(IQR 24.0-78.1)。大多数患者的主要诊断为恶性肿瘤(13 例,86.7%)。手术时间中位数为 5.5 小时(IQR 4.5-8.5),围手术期出血量中位数为 5000ml(IQR 2000-10000)。随访时的 MSTS 评分中位数为 63.3%(IQR 51.7-86.7%)。休息时的中位数 NRS 为 0.0(IQR 0.0-5.0),活动时的中位数 NRS 为 2.0(IQR 0.5-7.0),HOOS-PS 的中位数为 76.6%(IQR 67.9-91.0)。4 例患者出现与植入物相关的并发症(4 例,26.6%):1 例髋关节脱位(Henderson 1a 型),3 例结构并发症(3a 型),1 例深部感染(4a 型)和 1 例局部肿瘤复发(5b 型)。随访时,15 个植入物中有 4 个被归类为失败,植入物的存活率为 73.3%。

结论

在髋关节包括髋臼的半骨盆切除术后接受 3DPPI 重建的复杂患者中,可获得可接受的围手术期结果、功能结果、并发症发生率和短期植入物存活率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b14/10486168/e691c78e367e/10.1177_11207000221135068-fig1.jpg

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