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复方磺胺甲恶唑治疗神经型弓形虫病:10例报告

[Treatment of neurotoxoplasmosis with the combination sulfamethoxazole-trimethoprim: report of 10 cases].

作者信息

Nóbrega J P

机构信息

Divisão de Clínica Neurológica, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, Brasil.

出版信息

Arq Neuropsiquiatr. 1991 Sep;49(3):279-84. doi: 10.1590/s0004-282x1991000300008.

Abstract

Toxoplasmosis is the most frequent parasitic infection of the CNS in the immunocompromised host. When promptly treated with the sulfadiazine-pyrimethamine combination patients with cerebral toxoplasmosis characteristically respond with clear clinical and CT improvement within 1-2 weeks. We report the results achieved with the combination sulfamethoxazole-trimethoprim, and conclude that both combinations have similar effects in the treatment of CNS toxoplasmosis.

摘要

弓形虫病是免疫功能低下宿主中最常见的中枢神经系统寄生虫感染。当用磺胺嘧啶-乙胺嘧啶联合疗法及时治疗时,脑弓形虫病患者通常会在1至2周内出现明显的临床和CT改善。我们报告了磺胺甲恶唑-甲氧苄啶联合疗法取得的结果,并得出结论,两种联合疗法在治疗中枢神经系统弓形虫病方面具有相似的效果。

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