Nóbrega J P
Divisão de Clínica Neurológica, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, Brasil.
Arq Neuropsiquiatr. 1991 Sep;49(3):279-84. doi: 10.1590/s0004-282x1991000300008.
Toxoplasmosis is the most frequent parasitic infection of the CNS in the immunocompromised host. When promptly treated with the sulfadiazine-pyrimethamine combination patients with cerebral toxoplasmosis characteristically respond with clear clinical and CT improvement within 1-2 weeks. We report the results achieved with the combination sulfamethoxazole-trimethoprim, and conclude that both combinations have similar effects in the treatment of CNS toxoplasmosis.