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[巴贝斯虫病,一种鲜为人知的人畜共患病]

[Babesiosis, a little known zoonosis].

作者信息

Dvoraková Heroldová M, Dvorácková M

机构信息

Mikrobiologický ustav LF MU a FN u sv. Anny v Brnĕ.

出版信息

Epidemiol Mikrobiol Imunol. 2007 Nov;56(4):176-80.

Abstract

Babesiosis is an emerging tick borne zoonotic disease caused by intraerythrocytic parasites of the genus Babesia. Babesiosis is one of the most common infections of free-living animals worldwide but is perhaps most prevalent in rodents, carnivores, and cattle. This fact increases the concern about the emerging zoonosis. Like the malaria agent Plasmodium, the parasite Babesia attacks and damages the host's red cells. Babesia microti and Babesia divergens cause human infections. In the USA, an endemic region of this infection, most human cases are due to Babesia microti. In Europe, babesiosis is considerably rare and is caused by Babesia divergens, with splenectomized patients being at highest risk. The spectrum of disease is broad, ranging from an apparently silent infection to a fulminant, malaria-like disease. Symptoms include fever, chills and icterus. The treatment of choice is clindamycin and quinine. The laboratory diagnosis is based on direct detection of the parasite from blood smears. Due to increasing international travel, even relatively uncommon parasitic infections can be found in the Czech Republic and babesiosis is just one of them.

摘要

巴贝斯虫病是一种新出现的蜱传人畜共患病,由巴贝斯属的红细胞内寄生虫引起。巴贝斯虫病是全球自由生活动物中最常见的感染之一,但可能在啮齿动物、食肉动物和牛中最为普遍。这一事实增加了人们对这种新出现的人畜共患病的担忧。与疟原虫一样,巴贝斯虫寄生虫会攻击并损害宿主的红细胞。微小巴贝斯虫和分歧巴贝斯虫可导致人类感染。在美国这个该感染的流行地区,大多数人类病例是由微小巴贝斯虫引起的。在欧洲,巴贝斯虫病相当罕见,由分歧巴贝斯虫引起,脾切除患者风险最高。疾病谱很广,从明显无症状感染到暴发性、类似疟疾的疾病。症状包括发热、寒战和黄疸。首选治疗方法是克林霉素和奎宁。实验室诊断基于从血涂片直接检测寄生虫。由于国际旅行的增加,即使是相对罕见的寄生虫感染在捷克共和国也能被发现,巴贝斯虫病只是其中之一。

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