Tipu Salman Ahmed, Malik Hammad Afzal, Mohhayuddin Nazim, Sultan Gauhar, Hussain Manzoor, Hashmi Altaf, Naqvi Syed Ali Anwar, Rizvi Syed Adibul Hasan
Sindh Institute of Urology and Transplantation, Karachi.
J Pak Med Assoc. 2007 Sep;57(9):440-3.
To compare the efficacy of Holmium: YAG laser and pneumatic lithoclast in treating ureteric calculi.
The study included total of 100 patients divided into two equal groups of laser lithotripsy (LL) and pneumatic lithoclast (PL). Study was conducted between September 2006 and February 2007. Inclusion criteria were patients with a ureteric stone of size 1-2 cm and negative urine culture. An x-ray KUB was mandatory. IVU and CT pyelogram were also done when required. Procedures were done under general anaesthesia after a single dose of pre-operative antibiotic. A 7.5 Fr semi rigid ureteroscope was used for ureteroscopy in all cases. Holmium: YAG laser with 365 microm wide probe was employed in laser group and frequency was set between 5 and 10 Hz at a power of 10 to 15 W. Swiss lithoclast with single or multiple fire technique was used accordingly in PL group. Postoperatively patients underwent radiography and helical CT as required at 4th week of follow up to asses stone clearance.
The mean patient age in LL and PL group was 38 +/- 10 and 40 +/- 10 years respectively. The male to female ratio and stone size were similar between the groups. Stone migration up in pelvicalyceal system occurred in two patients of LL group while in eight patients of PL group. JJ Stent was placed in 5(10%) patients in laser group where as 13 (26%) patients required it in pneumatic lithoclast group. Stone free rate at 4 weeks was 92% in laser group as compared to 82% in pneumatic lithoclast group. Hospital stay was more than 24 hours in 2 patients of laser group as compared to 5 patients of pneumatic lithoclast group. Complication rate was 4% in LL group whereas it was 14% in PL group.
Holmium: YAG laser lithotripsy is a superior technology compared to pneumatic lithoclast in terms of rate of stone clearance and complications, especially in upper ureteric stones.
比较钬激光与气压弹道碎石术治疗输尿管结石的疗效。
本研究共纳入100例患者,分为激光碎石术(LL)和气压弹道碎石术(PL)两组,每组各50例。研究于2006年9月至2007年2月进行。纳入标准为输尿管结石大小为1 - 2 cm且尿培养阴性的患者。必须进行腹部平片(KUB)检查。必要时还需进行静脉肾盂造影(IVU)和CT肾盂造影。所有手术均在全身麻醉下进行,术前给予单剂量抗生素。所有病例均使用7.5 Fr半硬性输尿管镜进行输尿管镜检查。激光组使用直径365微米的钬激光探头,频率设定为5至10 Hz,功率为10至15 W。气压弹道碎石术组相应地使用具有单次或多次发射技术的瑞士气压弹道碎石机。术后患者在随访第4周时根据需要进行X线检查和螺旋CT检查以评估结石清除情况。
LL组和PL组患者的平均年龄分别为38±10岁和40±10岁。两组的男女比例和结石大小相似。LL组有2例患者出现结石向上移入肾盂肾盏系统,而PL组有8例。激光组有5例(10%)患者放置了双J支架,而气压弹道碎石术组有13例(26%)患者需要放置。激光组4周时的结石清除率为92%,而气压弹道碎石术组为82%。激光组有2例患者住院时间超过24小时,而气压弹道碎石术组有5例。LL组的并发症发生率为4%,而PL组为14%。
在结石清除率和并发症方面,钬激光碎石术相比气压弹道碎石术是一种更优的技术,尤其是对于上段输尿管结石。