Guelinckx P J
Catholic University Leuven, Belgium.
J Card Surg. 1991 Mar;6(1 Suppl):190-4. doi: 10.1111/jocs.1991.6.1s.190.
Muscle homograft transplantation and transposition have been performed to the heart, yet little data is available on the functional and structural changes after "simple transposition" of the latissimus dorsi (LD) muscle to the thoracic wall. Our aim was to compare the results of transplantation and transposition of the same muscle under experimental conditions. Five LD muscles were transposed to the anterior thoracic wall on an intact neurovascular pedicle. Five LD muscles were transplanted to the rectus femoris muscle site in the leg with microvascular techniques. Five control LD muscles were examined morphologically and functionally. The force measurements displayed a significant reduction in both experimental groups compared to control. The nearly 70% preservation of maximum isometric tension and the higher resistance to fatigue in the transplant support the concept of microneurovascular muscle transplantation to the heart. The experimental data also indicate that LD transpositions experience a significant reduction in force and mean fiber area despite an intact neural support.
已将肌肉同种异体移植和移位应用于心脏，但关于背阔肌（LD）“单纯移位”至胸壁后的功能和结构变化，现有数据很少。我们的目的是在实验条件下比较同一肌肉的移植和移位结果。将五块LD肌肉通过完整的神经血管蒂移位至胸前壁。采用微血管技术将五块LD肌肉移植至腿部股直肌部位。对五块对照LD肌肉进行形态学和功能检查。与对照组相比，两个实验组的力量测量结果均显示出显著降低。移植组中最大等长张力近70%的保留以及对疲劳的更高耐受性支持了向心脏进行微神经血管肌肉移植的概念。实验数据还表明，尽管有完整的神经支持，但LD移位后的力量和平均纤维面积仍显著降低。
