神经节苷脂的可能功能作用。

Possible functional role of gangliosides.

作者信息

Rahmann H

出版信息

Adv Exp Med Biol. 1976;71:151-61. doi: 10.1007/978-1-4614-4614-9_10.

Abstract

The brain ganglioside pattern of taxonomically close and distant related fish living at different temperatures were compared with the mammalian pattern. Furthermore the goldfish brain pattern was investigated after adaption (acclimitization, acclimation) to different temperatures. The results demonstrate correlations between body temperature and brain gangliosides: the lower the body temperature of animals, the higher the relative proportion of multi-sialo-gangliosides. The results are discussed with respect to the possible functional role of Ca++-ganglioside-complexes for the process of synaptic transmission.

摘要

将生活在不同温度下的分类学上相近和较远的鱼类的脑苷脂模式与哺乳动物的模式进行了比较。此外，在金鱼适应不同温度后，对其脑模式进行了研究。结果表明体温与脑苷脂之间存在相关性：动物的体温越低，多唾液酸脑苷脂的相对比例越高。针对Ca++-脑苷脂复合物在突触传递过程中可能的功能作用对结果进行了讨论。