食品和医疗设备中的邻苯二甲酸盐。
Phthalates in food and medical devices.
作者信息
Chou Karen, Wright Robert O
机构信息
Environmental Science and Policy Program, Department of Animal Science, Michigan State University, MI, USA.
出版信息
J Med Toxicol. 2006 Sep;2(3):126-35. doi: 10.1007/BF03161027.
Abstract
Phthalates are ubiquitous environmental chemicals with a broad range of potential adverse health effects. Exposure pathways include air, water, packaged food and household products. Biological effects include disruption of the balance of sex hormones, allergic reactions, and enzyme inhibition. Carcinogenicity is seen in animals. In human studies, phthalates have been associated with poorer sperm quality, the symptomatology of asthma, and shortened AGD. Given the widespread use of phthalates in industrialized countries, further research, particularly on birth outcomes, endocrine disruption and child development are greatly needed.
摘要
邻苯二甲酸盐是普遍存在的环境化学物质，具有广泛的潜在健康不良影响。接触途径包括空气、水、包装食品和家用产品。生物学效应包括破坏性激素平衡、过敏反应和酶抑制。在动物身上可见致癌性。在人体研究中，邻苯二甲酸盐与精子质量较差、哮喘症状和阴茎阴囊距离缩短有关。鉴于邻苯二甲酸盐在工业化国家的广泛使用，非常需要进一步开展研究，尤其是关于出生结局、内分泌干扰和儿童发育方面的研究。
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