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[精子质量参数分析的标准化与质量控制进展]

[Advances in standardization and quality control for the analysis of sperm quality parameters].

作者信息

Huang Yu-feng, Lu Jin-chun

机构信息

PLA Research Institute of Clinical Laboratory Medicine, Nanjing General Hospital of Nanjing Command, PLA, Nanjing, Jiangsu 210002, China.

出版信息

Zhonghua Nan Ke Xue. 2007 Nov;13(11):963-8.

Abstract

Semen analysis is a basic test to evaluate male reproductive function. In recent years, urgent needs for the standardization of semen analysis have been emphasized among andrologists worldwide. This review discusses the standardization and quality control (QC) for the analysis of sperm quality parameters, including sperm concentration, motility and morphology. The key to sperm concentration analysis is the standardization of sperm-counting chamber, thus Cell-VU chamber may be the first choice. The analysis of sperm motility and morphology is too subjective to be reliable. Therefore, the computer-aided semen analysis (CASA) system may be the final selection. QC of semen analysis mainly lies in the selection of QC materials and the administration of external QC and internal QC. Meanwhile, the charts and arithmetic methods should be established to monitor QC of semen analysis.

摘要

精液分析是评估男性生殖功能的一项基本检查。近年来,全球男科学专家都强调了精液分析标准化的迫切需求。本文综述了精子质量参数分析的标准化和质量控制(QC),包括精子浓度、活力和形态。精子浓度分析的关键在于精子计数室的标准化,因此Cell-VU计数室可能是首选。精子活力和形态分析主观性过强,难以可靠。因此,计算机辅助精液分析(CASA)系统可能是最终选择。精液分析的质量控制主要在于质量控制材料的选择以及外部质量控制和内部质量控制的实施。同时,应建立图表和计算方法以监测精液分析的质量控制。

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