Nmadu P T, Mabogunje O A
Department of Surgery, Ahmadu Bellow University Hospital, Zaria, Nigeria.
Cent Afr J Med. 1991 Aug;37(8):242-4.
From 1971 to 1985 at the Ahmadu Bello University Hospital, Zaria, 245 patients with multinodular goitre were operated upon mostly for cosmesis. Clinically unsuspected malignancy was present in 50 (20 pc) of the resected specimens of which 26 were follicular and 20 papillary. This pattern conforms with the reports from other African Zones of endemic goitre where the frequency of cancer is lower in the clinically solitary nodular goitre. Thus, the management strategy ought to regard the multinodular goitre as pre-malignant and operations should be performed earlier on this account.
1971年至1985年期间，在扎里亚的阿哈马杜·贝洛大学医院，245例患有多结节性甲状腺肿的患者接受了手术，主要目的是为了改善外观。在切除的标本中，有50例（20%）存在临床未怀疑的恶性肿瘤，其中26例为滤泡性，20例为乳头状。这种模式与其他非洲地方性甲状腺肿地区的报告相符，在这些地区，临床孤立性结节性甲状腺肿的癌症发生率较低。因此，管理策略应将多结节性甲状腺肿视为癌前病变，并应因此更早地进行手术。
