Maĭchuk Iu F, Lortkipanidze M M, Pozdniakova V V, Poazdniakov V I
Vestn Oftalmol. 2007 Sep-Oct;123(5):44-7.
Atopic keratoconjunctivitis (AKC) is presently considered as an individual nosological entity of ocular allergosis, which is associated with the systemic disease - atopic dermatitis. The clinical features of corneal lesions were studied in 40 patients with AKC. Those associated with the systemic pattern of an atopic process as a severe form of ocular allergosis were revealed. A classification of the clinical forms of corneal lesions in AKC as limbitis, epithelial microerosions, epithelial keratopathy, superficial keratitis in mild forms of the disease, is presented. The severe forms of AKC were characterized by corneal manifestations: extensive keratopathy, stromal keratitis with neovascularization without ulceration, corneal infiltrates and ulcers of bacterial and herpetic etiology.
特应性角结膜炎(AKC)目前被认为是眼部变态反应病中的一个独立病种,它与全身性疾病——特应性皮炎相关。对40例AKC患者的角膜病变临床特征进行了研究。发现这些病变与作为严重眼部变态反应病形式的特应性病程的全身性模式相关。本文提出了AKC角膜病变临床形式的分类,包括疾病轻度形式下的角膜缘炎、上皮微糜烂、上皮性角膜病变、浅层角膜炎。AKC的严重形式以角膜表现为特征:广泛的角膜病变、伴有新生血管形成但无溃疡的基质性角膜炎、细菌和疱疹性病因导致的角膜浸润和溃疡。