Delabays A
Service de médecine, Etablissement hospitalier de la Côte, Hôpital de Morges, chemin du Crêt 2, 1110 Morges.
Rev Med Suisse. 2007 Nov 14;3(133):2605-8.
This paper reviews the use of 3 biomarkers, BNP (brain natriuretic peptide), troponins and D-dimers, in 3 common clinical situations: the patient presenting with dyspnea, with chest pain or with syncope. The diagnostic utility and the pronostic implications of a positive as well as a negative test are reviewed according the most recent medical literature. Interpretation of false positive and false negative results is also discussed. Familiarity with the use of these tests is increasingly important because practicioners will be soon provided with rapid bed-side multi-markers assays to help them in their differential diagnosis while examining the patient.
本文综述了3种生物标志物,即脑钠肽(BNP)、肌钙蛋白和D-二聚体,在3种常见临床情况中的应用:出现呼吸困难、胸痛或晕厥的患者。根据最新医学文献,对阳性和阴性检测结果的诊断效用及预后意义进行了综述。还讨论了假阳性和假阴性结果的解读。熟悉这些检测的应用变得越来越重要,因为医生很快将能够使用快速床边多标志物检测,以在检查患者时帮助他们进行鉴别诊断。