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[叙利亚大马士革地区由硕大利什曼原虫MON-26引起的人类皮肤利什曼病]

[Human cutaneous leishmaniasis caused by Leishmania Major MON-26 in the region of Damascus (Syria)].

作者信息

Khiami A, Dereure J, Pratlong F, Martini A, Rioux J A

机构信息

Hôpital Mouassat, Laboratoire Central, Université de Damas, Syrie.

出版信息

Bull Soc Pathol Exot. 1991;84(4):340-4.

PMID:1807849
Abstract

In response to an epidemic of oriental sore around Damascus, an ecological and epidemiological survey was carried out in the village of Dmeir, 40 km NE of Damascus. Parasites isolated from six cases from Dmeir, and two other cases from Syria were identified as Leishmania major, zymodeme MON-26. This zymodeme is known as the agent of zoonotic cutaneous leishmaniasis from the Sub-Saharian Sahel to the Near and Middle East. This is the first report of L. major in Syria. In a group of 234 school children aged 5-11 years, the leishmanin skin test was positive in 37%, indicating a high transmission rate. The epidemic seems to be the result of agricultural and industrial development projects in the area: numbers of both the gerbil reservoir host and sandfly vector appear to be increased by the land improvement.

摘要

为应对大马士革周边地区东方疖的流行,在大马士革东北40公里处的德米尔村开展了一项生态与流行病学调查。从德米尔的6例病例以及叙利亚其他2例病例中分离出的寄生虫被鉴定为硕大利什曼原虫,酶带型为MON - 26。这种酶带型是从撒哈拉以南萨赫勒地区到近东和中东地区人畜共患皮肤利什曼病的病原体。这是叙利亚首次报告硕大利什曼原虫。在一组234名5至11岁的学童中,利什曼原虫皮肤试验阳性率为37%,表明传播率很高。此次流行似乎是该地区农业和工业发展项目所致:土地改良似乎使沙鼠储存宿主和白蛉传播媒介的数量均有所增加。

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