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MIRIAM资源:用于在系统生物学中生成和解析可靠交叉引用的工具。

MIRIAM Resources: tools to generate and resolve robust cross-references in Systems Biology.

作者信息

Laibe Camille, Le Novère Nicolas

机构信息

European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

出版信息

BMC Syst Biol. 2007 Dec 13;1:58. doi: 10.1186/1752-0509-1-58.

Abstract

BACKGROUND

The Minimal Information Requested In the Annotation of biochemical Models (MIRIAM) is a set of guidelines for the annotation and curation processes of computational models, in order to facilitate their exchange and reuse. An important part of the standard consists in the controlled annotation of model components, based on Uniform Resource Identifiers. In order to enable interoperability of this annotation, the community has to agree on a set of standard URIs, corresponding to recognised data types. MIRIAM Resources are being developed to support the use of those URIs.

RESULTS

MIRIAM Resources are a set of on-line services created to catalogue data types, their URIs and the corresponding physical URLs (or resources), whether data types are controlled vocabularies or primary data resources. MIRIAM Resources are composed of several components: MIRIAM Database stores the information, MIRIAM Web Services allows to programmatically access the database, MIRIAM Library provides an access to the Web Services and MIRIAM Web Application is a way to access the data (human browsing) and also to edit or add entries.

CONCLUSIONS

The project MIRIAM Resources allows an easy access to MIRIAM URIs and the associated information and is therefore crucial to foster a general use of MIRIAM annotations in computational models of biological processes.

摘要

背景

生化模型注释所需最小信息(MIRIAM)是一套针对计算模型注释和管理过程的指南,以促进其交换和重用。该标准的一个重要部分在于基于统一资源标识符对模型组件进行受控注释。为了实现这种注释的互操作性,社区必须就一组对应于公认数据类型的标准URI达成一致。正在开发MIRIAM资源以支持这些URI的使用。

结果

MIRIAM资源是一组在线服务,用于编目数据类型、其URI以及相应的物理URL(或资源),无论数据类型是受控词汇表还是原始数据资源。MIRIAM资源由几个组件组成:MIRIAM数据库存储信息,MIRIAM网络服务允许通过编程方式访问数据库,MIRIAM库提供对网络服务的访问,MIRIAM网络应用程序是一种访问数据(人工浏览)以及编辑或添加条目的方式。

结论

MIRIAM资源项目允许轻松访问MIRIAM URI及相关信息,因此对于在生物过程计算模型中推广使用MIRIAM注释至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/890b/2259379/231f6e0a0bd4/1752-0509-1-58-1.jpg

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