Mitchum Melissa G, Wang Xiaohong, Davis Eric L
University of Missouri, Division of Plant Sciences and Bond Life Sciences Center, Columbia, MO 65211, USA.
Curr Opin Plant Biol. 2008 Feb;11(1):75-81. doi: 10.1016/j.pbi.2007.10.010. Epub 2007 Dec 19.
The function of plant CLAVATA3 (CLV3)/ENDOSPERM SURROUNDING REGION (ESR) (CLE) peptides in shoot meristem differentiation has been expanded in recent years to implicate roles in root growth and vascular development among different CLE family members. Recent evidence suggests that nematode pathogens within plant roots secrete ligand mimics of plant CLE peptides to modify selected host cells into multinucleate feeding sites. This discovery demonstrated an unprecedented adaptation of an animal gene product to functionally mimic a plant peptide involved in cellular signaling for parasitic benefit. This review highlights the diverse and conserved role of CLE peptides in these different contexts.
近年来，植物CLAVATA3（CLV3）/胚乳周围区域（ESR）（CLE）肽在茎尖分生组织分化中的功能已得到扩展，不同的CLE家族成员在根生长和维管发育中也发挥作用。最近的证据表明，植物根内的线虫病原体会分泌植物CLE肽的配体模拟物，将选定的宿主细胞转变为多核取食位点。这一发现表明，一种动物基因产物为了寄生利益在功能上模拟参与细胞信号传导的植物肽，这是前所未有的适应性表现。本综述着重介绍了CLE肽在这些不同背景下的多样且保守的作用。
