Hardy P
Service de Psychiatrie d'Adultes, CHU de Bicêtre.
Encephale. 1991 Dec;17 Spec No 3:351-9.
The influence of psychosocial factors on the incidence and evolution of depressive illness is well established. The joint study of different aspects of the psychosocial field involved in the risk of depressive illness substantiated interactions between these various factors, modulating the risk of depression. Several psychosocial models of depression, as Harris and Brown's model, have taken into account those interactions, discriminating vulnerability factors and precipitating factors (stressful life events, lasting difficulties): vulnerability factors, not inducing depression per se, increase the depressing effect of precipitating factors when both factors happen to be combined. However the validity of those models has to be confirmed, and mechanisms underlying interactions between psychosocial factors call for further elucidation. Other studies will also have to specify the role of psychological and biological variables in the way psychosocial factors interfere with the occurrence of depression.
社会心理因素对抑郁症发病率及病程的影响已得到充分证实。对抑郁症风险所涉及的社会心理领域不同方面进行联合研究,证实了这些不同因素之间的相互作用,调节着抑郁症风险。几种抑郁症的社会心理模型,如哈里斯和布朗的模型,已考虑到这些相互作用,区分了易患因素和促发因素(应激性生活事件、长期困难):易患因素本身不会诱发抑郁症,但当这两种因素同时出现时,会增强促发因素的致郁作用。然而,这些模型的有效性还有待证实,社会心理因素之间相互作用的潜在机制也需要进一步阐明。其他研究还必须明确心理和生物学变量在社会心理因素干扰抑郁症发生过程中的作用。