Tada Yuji, Takiguchi Yuichi, Terada Jiro, Yoshida Takako, Shinozaki Aya, Sakao Seiichiro, Kasahara Yasunori, Kurosu Katsushi, Tanabe Nobuhiro, Tatsumi Koichiro, Hiroshima Kenzo, Kuriyama Takayuki
Dept. of Respirology, Graduate School of Medicine, Chiba University.
Gan To Kagaku Ryoho. 2007 Dec;34(13):2275-7.
A 60-year-old man was admitted to our hospital complaining of back pain and bloody sputum. Chest CT scan showed characteristic multiple small nodules with central dense opacity and surrounding faint opacity, suggesting lesions with hemorrhage. Bone scintigram and MRI revealed multiple osteolytic lesions in pelvis and lumbar spine. Biopsy of the bone lesion established a diagnosis of angiosarcoma. Chemotherapy with paclitaxel and palliative radiotherapy for the bone were initiated. Pulmonary metastases dramatically diminished after 4 courses of paclitaxel treatment. After eight weeks, the tumor recurred. Salvage chemotherapy of weekly administration of docetaxel yielded limited effects. The patient died of cancer one year after treatment initiation.
一名60岁男性因背痛和咯血入住我院。胸部CT扫描显示有特征性的多个小结节,中央密度增高,周围密度模糊,提示有出血性病变。骨闪烁显像和磁共振成像显示骨盆和腰椎有多个溶骨性病变。骨病变活检确诊为血管肉瘤。开始使用紫杉醇进行化疗,并对骨病变进行姑息性放疗。4个疗程的紫杉醇治疗后,肺转移灶明显缩小。8周后,肿瘤复发。每周使用多西他赛进行挽救性化疗效果有限。患者在开始治疗一年后死于癌症。