Department of Ophthalmology. Hadassah Medical Center. Jerusalem. Israel; *Department of Ophthalmology, University of Florida. Gainesville. Florida; and †Department of Ophthalmology and Visual Sciences. Washington University School of Medicine. St. Louis. Missouri, U.S.A.
J Glaucoma. 1992 Winter;1(4):228-32. doi: 10.1097/00061198-199201040-00003.
We report our experience with Molteno implants in 27 eyes of 20 children with glaucoma. Associated ocular findings included Sturge Weber syndrome (one patient), aniridia and retinoschisis (one patient), aphakia (seven patients, eight eyes), rubella syndrome (two patients), Peters anomaly (one patient), and Treacher Collins syndrome (one patient). Fifteen eyes received a single-plate implant, and 12 eyes received a double-plate implant in two stages. The patients' ages ranged from 2 months to 13 years (mean 47 +/- 55 months). The average number of previous glaucoma procedures was four per eye (range two to 10). The follow-up period ranged from 6 to 36 months (mean 20 +/- 9 months). The mean intraocular pressure before surgery was 34 +/- 4 mm Hg. The mean postoperative intraocular pressure was 19 +/- 11 mm Hg at 1 month and 19 +/- 6 mm Hg at 1 year (p < 0.001 at both times). After surgery nine eyes (33.3%) required no medication for control of intraocular pressure. Additional surgery was required in 12 eyes (44.4%). We believe the Molteno implant is a useful approach for children with glaucoma who fail to respond to standard medical and surgical treatments.
我们报告了 20 例儿童 27 只眼的青光眼使用 Molteno 植入物的经验。相关的眼部发现包括 Sturge-Weber 综合征（1 例）、无虹膜和视网膜劈裂（1 例）、无晶状体（7 例，8 只眼）、风疹综合征（2 例）、Peters 异常（1 例）和 Treacher Collins 综合征（1 例）。15 只眼接受了单盘植入物，12 只眼分两期接受了双盘植入物。患者年龄从 2 个月至 13 岁（平均 47 +/- 55 个月）。每只眼的平均先前青光眼手术次数为 4 次（范围 2 至 10 次）。随访时间从 6 至 36 个月（平均 20 +/- 9 个月）。术前平均眼压为 34 +/- 4mmHg。术后 1 个月平均眼压为 19 +/- 11mmHg，术后 1 年平均眼压为 19 +/- 6mmHg（两次均<0.001）。手术后，9 只眼（33.3%）无需药物控制眼压。12 只眼（44.4%）需要进一步手术。我们认为 Molteno 植入物是对标准药物和手术治疗反应不佳的儿童青光眼的一种有用方法。
