*Department of Ophthalmology, The New York Eye and Ear Infirmary, New York, New York, U.S.A., and †Department of Ophthalmology, Jewish General Hospital and McGill University, Montreal, Quebec, Canada.
J Glaucoma. 1992 Winter;1(4):243-7. doi: 10.1097/00061198-199201040-00006.
A patient with Weill-Marchesani syndrome and angle-closure glaucoma had persistent appositional closure after laser iridotomy that was unrelieved by topical application of either miotic or cycloplegic agents. Argon laser peripheral iridoplasty successfully opened the angle. The patient's sister also had Weill-Marchesani syndrome and angle closure unrelieved by laser iridotomy. Angle closure in Weill-Marchesani syndrome and the response to laser iridotomy and treatment with either miotic or cycloplegic agents may be complex and depends on the relative proportion of pupillary block as a mechanism underlying the angle closure, the functional status of the zonular apparatus, and the degree of angle crowding by the peripheral iris in the presence or absence of peripheral anterior synechiae.
一位患有 Weill-Marchesani 综合征和闭角型青光眼的患者，在激光虹膜切开术后存在持续的前粘连性关闭，局部应用缩瞳剂或睫状肌麻痹剂均无法缓解。氩激光周边虹膜成形术成功地开放了房角。该患者的姐姐也患有 Weill-Marchesani 综合征和激光虹膜切开术后未缓解的闭角型青光眼。Weill-Marchesani 综合征中的闭角型青光眼以及对激光虹膜切开术和缩瞳剂或睫状肌麻痹剂的反应可能很复杂，取决于瞳孔阻滞作为闭角型青光眼发病机制的相对比例、悬韧带的功能状态以及周边虹膜是否存在周边前粘连引起的房角拥挤程度。
