一项对于理解艾滋病毒传播具有开创性的发现。
A seminal finding for understanding HIV transmission.
作者信息
Roan Nadia R, Greene Warner C
机构信息
Gladstone Institute of Virology and Immunology, University of California, San Francisco, 1650 Owens Street, San Francisco, CA 94158, USA.
出版信息
Cell. 2007 Dec 14;131(6):1044-6. doi: 10.1016/j.cell.2007.11.030.
PMID:18083095
Abstract
Although the worldwide incidence of HIV infection is high, the retrovirus displays a surprisingly low infectivity in vitro. As a potential explanation for this discrepancy, Münch et al. (2007) now identify and characterize a factor found in human semen that under certain conditions can enhance HIV infectivity by more than 100,000-fold.
摘要
尽管全球范围内HIV感染的发生率很高，但这种逆转录病毒在体外的感染性却出奇地低。作为对这种差异的一种潜在解释，明希等人（2007年）现在鉴定并描述了一种在人类精液中发现的因子，在某些条件下，它可将HIV的感染性提高超过10万倍。
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