Mocan Mehmet C, Ozgen Burce, Irkec Murat
Department of Ophthalmology, Hacettepe University School of Medicine, Ankara, Turkey.
J AAPOS. 2008 Apr;12(2):210-1. doi: 10.1016/j.jaapos.2007.09.009. Epub 2007 Dec 21.
A 15-month-old girl was referred for evaluation of congenital absence of both eyelids. Clinical evaluation revealed bilateral total cryptophthalmos and enlarged globes in addition to genitourinary anomalies, umbilical hernia, renal agenesis, and facial anomalies. The clinical findings were consistent with Fraser syndrome. Magnetic resonance imaging of the orbits revealed dysplastic globes that were characterized by cystic expansions that extended laterally anterior to the lateral orbital rim. Bilateral orbito-palpebral cysts that communicate with a dysplastic globe and extend beyond the orbital cavity may be a rare presenting feature of Fraser syndrome.
