Taşkaya Yaylali Olga, Suna Kiraç Fatma, Yaylali Volkan, Gündüz Kaan, Düzcan Ender
Pamukkale Universitesi Hastanesi, Nükleer Tip Anabilim Dali, Doktorlar cad. No: 42 20100, Denizli, Turkey.
Hell J Nucl Med. 2007 Sep-Dec;10(3):160-3.
We describe marginal zone lymphoma of the mucosa-associated lymphoid tissue (MALT) and especially MALT lymphoma occurring in the conjunctiva. Tumors of the conjunctiva and cornea are grouped into two major categories of congenital and acquired lesions. Lymphoid tumors of the conjunctiva are acquired tumors and can occur as an isolated lesion or can be a manifestation of systemic lymphoma. Primary lymphomas of the conjunctiva are extremely rare usually originate from extranodal marginal zone B-cell non-Hodgkin's lymphomas of MALT and occur among older adults with a mean age of 61 years. In the last decade it has been reported that MALT lymphomas may develop in various extraintestinal locations, sometimes even without the presence of a mucosa. Half of MALT lymphomas occur in the gastrointestinal tract. MALT lymphomas of the eye are rare and originate from the conjunctiva and the lacrimal glands. Studies evaluating the clinical impact of 67Ga-C scintigraphy for MALT-type lymphomas imaging are rare, based on small numbers, heterogenous groups of patients. Clinical examination, excisional biopsy, histopathology and immunohistochemical studies, computerized tomography and magnetic resonance imaging are also used for the diagnosis of cunjunctival MALT disease. A case of ours gives reason for further discussion. Treatment and follow-up of MALT lymphoma is described.
我们描述了黏膜相关淋巴组织（MALT）边缘区淋巴瘤，尤其是发生于结膜的MALT淋巴瘤。结膜和角膜肿瘤分为先天性和后天性病变两大类。结膜淋巴瘤属于后天性肿瘤，可表现为孤立性病变，也可为系统性淋巴瘤的一种表现形式。结膜原发性淋巴瘤极为罕见，通常起源于MALT的结外边缘区B细胞非霍奇金淋巴瘤，好发于平均年龄61岁的老年人。在过去十年中，有报道称MALT淋巴瘤可发生于各种肠道外部位，有时甚至不存在黏膜。半数MALT淋巴瘤发生于胃肠道。眼部MALT淋巴瘤罕见，起源于结膜和泪腺。基于少量、异质性患者群体，评估67Ga - C闪烁扫描对MALT型淋巴瘤成像临床影响的研究很少。临床检查、切除活检、组织病理学和免疫组化研究、计算机断层扫描和磁共振成像也用于结膜MALT疾病的诊断。我们的一个病例值得进一步探讨。文中还描述了MALT淋巴瘤的治疗及随访情况。
