Iwanaga M, Ichinose Y
Department of Bacteriology, University of the Ryukyus School of Medicine, Okinawa, Japan.
Microbiol Immunol. 1991;35(9):705-15. doi: 10.1111/j.1348-0421.1991.tb01604.x.
An aberrant hemolysin produced by a Vibrio cholerae non-O1 strain N037 (N037-hly) was purified and characterized. N037-Hly was antigenically very similar to El Tor hemolysin but differed in molecular weight (48,000 vs. 60,000), interaction with glucose, and hemolytic activity. Of 100 V. cholerae non-O1 strains other than the N037 strain examined, none produced this aberrant hemolysin. The N-terminal amino acid sequence of N037-hly was highly homologous to that of El Tor hemolysin.
霍乱弧菌非O1菌株N037产生的一种异常溶血素(N037-hly)被纯化并进行了特性鉴定。N037-Hly在抗原性上与埃尔托溶血素非常相似,但在分子量(48,000对60,000)、与葡萄糖的相互作用以及溶血活性方面存在差异。在所检测的除N037菌株外的100株霍乱弧菌非O1菌株中,没有一株产生这种异常溶血素。N037-hly的N端氨基酸序列与埃尔托溶血素的高度同源。