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针对癌症患者的心理干预随机对照试验:I. 改变机制

RCT of a psychological intervention for patients with cancer: I. mechanisms of change.

作者信息

Andersen Barbara L, Shelby Rebecca A, Golden-Kreutz Deanna M

机构信息

Department of Psychology, Ohio State University.

出版信息

J Consult Clin Psychol. 2007 Dec;75(6):927-38. doi: 10.1037/0022-006X.75.6.927.

Abstract

Little is known about the therapeutic processes contributing to efficacy of psychological interventions for patients with cancer. Data from a randomized clinical trial yielding robust biobehavioral and health effects (B. L. Andersen et al., 2004, 2007) were used to examine associations between process variables, treatment utilization, and outcomes. Novel findings emerged. Patients were highly satisfied with the treatment, but their higher levels of felt support (group cohesion) covaried with lower distress and fewer symptoms. Also, specific treatment strategies were associated with specific outcomes, including lower distress, improved dietary habits, reduced symptomatology, and higher chemotherapy dose intensity. These data provide a comprehensive test of multiple therapeutic processes and mechanisms for biobehavioral change with an intervention including both intensive and maintenance phases.

摘要

对于癌症患者心理干预疗效的治疗过程,我们所知甚少。一项产生了强大生物行为和健康效应的随机临床试验(B. L. 安德森等人,2004年,2007年)的数据被用于检验过程变量、治疗利用情况和结果之间的关联。出现了新的发现。患者对治疗高度满意,但他们较高的感知支持水平(群体凝聚力)与较低的痛苦程度和较少的症状相关。此外,特定的治疗策略与特定的结果相关,包括较低的痛苦程度、改善的饮食习惯、减轻的症状以及更高的化疗剂量强度。这些数据对一种包括强化和维持阶段的干预措施中生物行为改变的多种治疗过程和机制进行了全面检验。

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