Saied G M, Kamel R M, Dessouki N
Department of General Surgery, Faculty of Medicine, Cairo University, Egypt.
Tanzan Health Res Bull. 2007 Sep;9(3):196-201.
One of the successful treatments for cyclical mastalgia is bromocriptine evening primrose combination. A double blind study was applied on 80 patients with cyclical mastalgia. They were randomly divided into two groups (A and B). In group A, patients were treated by bromocriptine/evening primrose. To group B, LILT with specified dosimetry was applied, using a device that delivers He-Ne laser combined with 4 infra-red diode laser. Evaluation of treatment was both subjective (using VAS) and objective (studying the degree of drop in plasma cortisol level). The drop of plasma cortisol with treatment was studied using the student -t distribution. A good response was observed in the laser group in 82.5%, compared to 63.9% in the bromocriptine/evening primrose group. There was a significant deference before and after treatment in both groups (P<0.05). This difference was more for the drug treated group than for the laser treated group, but in the latter, it acted on a wider sector of patients. In conclusion, LILT is recommended as a new treatment modality for cyclical mastalgia.
治疗周期性乳腺疼痛的一种成功疗法是溴隐亭与月见草的联合使用。对80例周期性乳腺疼痛患者进行了一项双盲研究。他们被随机分为两组（A组和B组）。A组患者采用溴隐亭/月见草进行治疗。B组使用一种能发射氦氖激光和4个红外二极管激光的设备，采用特定剂量的低强度激光疗法（LILT）。治疗评估包括主观评估（使用视觉模拟评分法[VAS]）和客观评估（研究血浆皮质醇水平下降程度）。使用学生t分布研究治疗后血浆皮质醇的下降情况。激光组有82.5%的患者反应良好，相比之下，溴隐亭/月见草组为63.9%。两组治疗前后均有显著差异（P<0.05）。药物治疗组的这种差异比激光治疗组更大，但在激光治疗组中，它作用于更广泛的患者群体。总之，低强度激光疗法被推荐为治疗周期性乳腺疼痛的一种新的治疗方式。
