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在静息状态下的人体中,肺气体交换会因心血管潜水反应而降低。

Pulmonary gas exchange is reduced by the cardiovascular diving response in resting humans.

作者信息

Andersson Johan P A, Biasoletto-Tjellström Gustaf, Schagatay Erika K A

机构信息

Department of Cell and Organism Biology, Lund University, Lund, Sweden.

出版信息

Respir Physiol Neurobiol. 2008 Feb 29;160(3):320-4. doi: 10.1016/j.resp.2007.10.016. Epub 2007 Nov 7.

DOI:10.1016/j.resp.2007.10.016
PMID:18088568
Abstract

The diving response reduces the pulmonary O(2) uptake in exercising humans, but it has been debated whether this effect is present at rest. Therefore, respiratory and cardiovascular responses were recorded in 16 resting subjects, performing apnea in air and apnea with face immersion in cold water (10 degrees C). Duration of apneas were predetermined to be identical in both conditions (average: 145 s) and based on individual maximal capacity (average: 184 s). Compared to apnea in air, an augmented diving response was elicited by apnea with face immersion. The O(2) uptake from the lungs was reduced compared to the resting eupneic control (4.6 ml min(-1)kg(-1)), during apnea in air (3.6 ml min(-1)kg(-1)) and even more so during apnea with face immersion (3.4 ml min(-1)kg(-1)). We conclude that the cardiovascular adjustments of the diving response reduces pulmonary gas exchange in resting humans, allowing longer apneas by preserving the lungs' O(2) store for use by vital organs.

摘要

潜水反应会降低运动人群的肺氧摄取,但静息时是否存在这种效应一直存在争议。因此,对16名静息受试者进行了呼吸和心血管反应记录,他们分别在空气中屏气以及面部浸入冷水中(10摄氏度)屏气。两种情况下的屏气持续时间预先设定为相同(平均:145秒),并基于个体最大能力(平均:184秒)。与在空气中屏气相比,面部浸入冷水中屏气引发了更强的潜水反应。与静息时平稳呼吸的对照组(4.6毫升·分钟-1·千克-1)相比,在空气中屏气时肺氧摄取减少(3.6毫升·分钟-1·千克-1),面部浸入冷水中屏气时减少得更多(3.4毫升·分钟-1·千克-1)。我们得出结论,潜水反应的心血管调节会降低静息人群的肺气体交换,通过保存肺部的氧储备以供重要器官使用,从而允许更长时间的屏气。

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