Glowacki Julie
Harvard Medical School, Boston, MA, USA.
Oral Maxillofac Surg Clin North Am. 2007 May;19(2):187-98, vi. doi: 10.1016/j.coms.2007.01.001.
With aging, there is a loss of skeletal mass in women and men, but the rate of loss accelerates in perimenopausal women. With the loss of bone mass there is increased risk for fracture in the axial and appendicular skeleton. The mandible and maxilla also experience age-related declines in some parameters of architecture and trabecular pattern, but those do not seem to be directly associated with fracture risk. Although the literature is controversial regarding the generalizability of the impact of systemic osteoporosis on the oral/maxillofacial patient, it is prudent to give consideration to an individual patient's osteoporosis status, risk, and anti-osteoporosis therapies when planning oral and maxillofacial surgical procedures.
随着年龄增长，男性和女性都会出现骨量流失，但围绝经期女性的骨量流失速度会加快。随着骨量的流失，中轴骨和四肢骨骼发生骨折的风险增加。下颌骨和上颌骨在结构和小梁模式的某些参数方面也会出现与年龄相关的衰退，但这些似乎与骨折风险没有直接关联。尽管关于全身性骨质疏松症对口腔/颌面患者影响的普遍性，文献存在争议，但在规划口腔颌面外科手术时，考虑个体患者的骨质疏松症状况、风险和抗骨质疏松治疗是谨慎的做法。
