Singh Sarman, Sankar Manimuthu Mani, Gopinath Krishnamoorthy
Division of Clinical Microbiology, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi-110 029, India.
AIDS. 2007 Nov 12;21(17):2345-7. doi: 10.1097/QAD.0b013e3282f125c9.
Fifty-four full-blown AIDS patients suspected of having HIV-tuberculosis co-infection were investigated for the prevalence of extensively drug-resistant (XDR) Mycobacterium tuberculosis. Out of the 54 patients, M. tuberculosis was isolated from 24 (44.4%). Twelve (50%) isolates of these had resistance to first-line drugs, whereas four (33.33%) were also resistant to second-line drugs. All four patients, in whom XDR M. tuberculosis was isolated, died within 2.6 months of diagnosis.
对54名疑似合并感染人类免疫缺陷病毒（HIV）和结核的典型艾滋病患者进行了广泛耐药结核分枝杆菌患病率调查。在这54名患者中，24名（44.4%）分离出结核分枝杆菌。其中12株（50%）对一线药物耐药，而4株（33.33%）对二线药物也耐药。所有分离出广泛耐药结核分枝杆菌的4名患者在诊断后2.6个月内死亡。
