Gurney Theresa A, Orloff Lisa A
Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, San Francisco, California 94115, USA.
Laryngoscope. 2008 Feb;118(2):243-6. doi: 10.1097/MLG.0b013e31815a9e9d.
To demonstrate the efficacy of otolaryngologist-head and neck surgeon-performed ultrasonography (US) for the preoperative localization of parathyroid adenomas.
A retrospective chart review of all patients evaluated by office-based US for the localization of surgery-proven parathyroid adenomas from October 2004 through February 2007.
A total of 29 patients underwent preoperative US localization. Twenty-three (79%) were females, and six (21%) were males. The age of patients ranged from 27 to 85 years of age. The size range of adenomas detected as measured by US was 0.5 to 2.7 cm. Pathology specimen measurements ranged from 0.3 to 3.4 cm. A total of 30 parathyroid adenomas were found. US identified 90% of the parathyroid adenomas to the correct side, left or right. In addition, US localized the parathyroid adenomas to the correct quadrant, superior or inferior, 83% of the time. Challenges in accurate localization were associated with patient obesity, presence of thyroid carcinoma, and multinodular thyroid disease. For comparison, sestamibi scans performed on the same patients localized the parathyroid adenoma to the correct side only 71% of the time and to the correct quadrant 61% of the time.
Otolaryngologist-head and neck surgeon-performed US can accurately identify the location of parathyroid adenomas and is a useful tool for preoperative planning.
证明耳鼻喉头颈外科医生进行的超声检查(US)在甲状旁腺腺瘤术前定位中的有效性。
对2004年10月至2007年2月期间所有通过门诊超声检查评估以定位经手术证实的甲状旁腺腺瘤的患者进行回顾性病历审查。
共有29例患者接受了术前超声定位。其中23例(79%)为女性,6例(21%)为男性。患者年龄在27至85岁之间。超声检测到的腺瘤大小范围为0.5至2.7厘米。病理标本测量范围为0.3至3.4厘米。共发现30个甲状旁腺腺瘤。超声将90%的甲状旁腺腺瘤定位到正确的一侧,即左侧或右侧。此外,超声将甲状旁腺腺瘤定位到正确象限(上或下)的时间占83%。准确定位的挑战与患者肥胖、甲状腺癌的存在以及甲状腺结节性疾病有关。作为比较,对同一患者进行的 sestamibi 扫描仅在71%的时间将甲状旁腺腺瘤定位到正确的一侧,在61%的时间定位到正确的象限。
耳鼻喉头颈外科医生进行的超声检查能够准确识别甲状旁腺腺瘤的位置,是术前规划的有用工具。