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多囊卵巢综合征女性的心血管风险

Cardiovascular risk in women with polycystic ovary syndrome.

作者信息

Cho L W, Atkin S L

机构信息

Department of Medicine, University of Hull, Hull, UK.

出版信息

Minerva Endocrinol. 2007 Dec;32(4):263-73.

PMID:18091663
Abstract

Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women that has received an immense amount of attention in the recent years due to the possible associated risk of cardiovascular disease. Women with PCOS demonstrate an adverse cardiovascular profile characteristic of the cardiometabolic syndrome and an established risk of progression to type 2 diabetes. Despite the presence of cardiovascular risk factors and increased surrogate markers of cardiovascular disease, it is unclear if they develop accelerated atherosclerosis. This article summarized the recent development and findings of cardiovascular risk in women with PCOS, and finally the therapeutic options will be discussed.

摘要

多囊卵巢综合征(PCOS)是女性常见的内分泌紊乱疾病,近年来由于其可能伴发的心血管疾病风险而受到了极大关注。患有PCOS的女性表现出心血管代谢综合征特有的不良心血管特征以及发展为2型糖尿病的既定风险。尽管存在心血管危险因素且心血管疾病的替代标志物增加,但尚不清楚她们是否会发展为加速动脉粥样硬化。本文总结了PCOS女性心血管风险的最新进展和研究结果,最后将讨论治疗选择。

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Cardiovascular risk in women with polycystic ovary syndrome.多囊卵巢综合征女性的心血管风险
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Obesity and polycystic ovary syndrome.肥胖与多囊卵巢综合征。
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2
Developmental programming: excess weight gain amplifies the effects of prenatal testosterone excess on reproductive cyclicity--implication for polycystic ovary syndrome.发育编程:体重过度增加会放大产前睾酮过多对生殖周期的影响——对多囊卵巢综合征的启示。
Endocrinology. 2009 Mar;150(3):1456-65. doi: 10.1210/en.2008-1256. Epub 2008 Oct 30.
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The metabolic syndrome.代谢综合征
Endocr Rev. 2008 Dec;29(7):777-822. doi: 10.1210/er.2008-0024. Epub 2008 Oct 29.